Purpose
1) To determine if the combined incidence of non-fatal myocardial infarction (MI) and coronary heart disease (CHD) death differs
between diuretic based treatments and each of three selected alternative antihypertensive pharmacological treatments
2) To determine in a subset of this population if lowering serum cholesterol with a HMG CoA reductase inhibitor in older adults
reduces all cause mortality compared to a control group receiving usual care
References
Davis BR, et al & Hawkins CM: For the ALLHAT Research Group: Rationale and design for the Antihypertensive and
Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Am J Hypertens 1996, 9:342-360. |