Purpose
To determine whether in hypertensive patients aged 65-84 there is any difference in total CV events (fatal and non-fatal) between
antihypertensive treatment with an angiotensin converting enzyme (ACE) inhibitor-based regimen and treatment with a
diuretic-based regimen over a 5 year period
References
Management Committee on behalf of the High Blood Pressure
Research Council of Australia: Australian comparative outcome trial of angiotensin converting enzyme inhibitor- and
diuretic-based treatment of hypertension in the elderly (ANBP2): objectives and protocol. Clin Exp Pharmacol Physiol
1997, 24:188-192.
Reid CM, et al & West MJ: Feasibility of conducting cardiovascular outcome research in Australian general practice:
results from the ANBP2 pilot study. Australian National Blood Pressure Study. Clin Exp Pharmacol Physiol 1997,
24:370-373. |