Purpose
To determine the most effective single-agent therapy for reducing the frequency and duration of episodes of asymptomatic
ischaemia in patients with stable exertional angina
References
Stone PH, Gibson RS, Glasser SP, et al: Comparison of propranolol, diltiazem, and nifedipine in the treatment of
ambulatory ischaemia in patients with stable angina. Differential effects on ambulatory ischaemia, exercise
performance, and anginal symptoms. Circulation 1990, 82:1962–1972.
Andrews TC, Fenton T, Toyosaki N, et al: Subsets of ambulatory myocardial ischemia based on heart rate activity.
Circadian distribution and response to anti-ischemic medication. Circulation 1993, 88:92–100.
Borzak S, Fenton T, Glasser SP, et al: Discordance between effects of anti-ischemic therapy on ambulatory ischemia,
exercise performance and anginal symptoms in patients with stable angina pectoris. J Am Coll Cardiol 1993,
21:1605–1611.
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Farmacêutica