Purpose
To assess the influence of frequency and duration of symptomatic and asymptomatic ischaemic episodes on the occurrence of
fatal and non-fatal cardiac events and to analyse the response to atenolol treatment
References
Pepine CJ, Cohn PF, Deedwania PC, et al: The prognostic and economic implications of a strategy to detect and treat
asymptomatic ischemia: the atenolol silent ischemia trial (ASIST) protocol. Clin Cardiol 1991, 14:457–462.
Pepine CJ, Cohn PF, Deedwania PC, et al: Effects of treatment on outcome in mildly symptomatic patients with
ischemia during daily life. The Atenolol Silent Ischemia Study (ASIST). Circulation 1994, 90:762–768.
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Farmacêutica