Purpose
1. To assess whether the combination of aspirin and anticoagulant (AC) therapy is superior to either agent alone in reducing the
frequency of recurrent myocardial ischaemia and the need for coronary angioplasty or coronary artery bypass surgery 2. To
assess whether the combination of aspirin plus anticoagulation vs aspirin alone, when added to conventional anti-anginal
therapy, reduces cardiac morbidity and mortality in non-prior aspirin users.
References
Cohen M, Adams PC, Hawkins L, et al: Usefulness of antithrombotic therapy in resting angina pectoris or non-Q-wave
myocardial infarction in preventing death and myocardial infarction (a pilot study from the Antithrombotic Therapy
in Acute Coronary Syndromes Study Group). Am J Cardiol 1990, 66:1287–1292.
Cohen M, Adams PC, Parry G, et al: Combination antithrombotic therapy in unstable rest angina and non-Q-wave
infarction in nonprior aspirin users: primary end points analysis from the ATACS trial. Circulation 1994, 89:81–88.
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Farmacêutica