Purpose
To investigate the effects of antioxidant supplements on the incidence of heart disease (the original study looked primarily at
the incidence of lung cancer)
References
The ATBC Cancer Prevention Study Group: The alpha-tocopherol, beta-carotene lung cancer prevention study: design,
methods, participant characteristics, and compliance. Ann Epidemiol 1994, 4:1-10.
Rapola JM, et al & Huttunen JK: Effect of vitamin E and beta carotene on the incidence of angina pectoris. A
randomized, double-blind, controlled trial. JAMA 1996, 275:693-698.
Rapola JM, et al & Heinonen OP: Randomised trial of alpha-tocopherol and beta-carotene supplements on incidence
of major coronary events in men with previous myocardial infraction. Lancet 1997, 349:1715-1720. |
Farmacêutica