Purpose
To determine whether daily administration of propranolol after myocardial infarction (MI) results in a significant reduction in
mortality from all causes during a 2–4-year follow-up period
Secondary objectives: to determine the effect of propranolol on coronary heart disease (CHD) mortality, sudden cardiac death
(SCD) and CHD mortality + definite non-fatal MI
References
The BHAT research group: A randomised trial of propranolol in patients with acute myocardial infarction. I. Mortality
results. JAMA 1982, 247:1707–1714.
The BHAT research group: A randomised trial of propranolol in patients with acute myocardial infarction. II. Morbidity
results. JAMA 1983, 250:2814–2819.
Viscoli CM, Horwitz RI, Singer BH: Beta-blockers after myocardial infarction: influence of first-year clinical course on
long-term effectiveness. Ann Intern Med 1992, 118:99–110.
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Farmacêutica