COLUMBUS
Low-molecular weight heparin in the treatment of patients with venous thromboembolism

Purpose
To determine whether fixed-dose, subcutaneous low-molecular weight heparin and adjusted-dose, continuous intravenous unfractionated heparin have at least equivalent efficacy in unselected patients with symptomatic VTE

References
The COLUMBUS investigators: Low-molecular weight heparin in the treatment of patients with venous thromboembolism. N Engl J Med 1997, 337:657-662.

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Apoio: Libbs Farmacêutica Farmacêutica